Original publikationer
2025. Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): a European, randomised, placebocontrolled, primary prevention trial (PDF, 1,14 MB, nytt fönster).
Anette-Gabriele Ziegler, Peter Achenbach, Andreas Weiß, Reinhard Berner, Kristina Casteels, Helena Elding Larsson, Florian Haupt, Angela Hommel, An Jacobs, Olga Kordonouri, Markus Lundgren, Mariusz Ołtarzewski, Markus Pfirrmann, Matthew D Snape, Agnieszka Szypowska, John A Todd, Manu Vatish, Thekla von dem Berge, Christiane Winkler, Ezio Bonifacio, GPPAD-POInT Study Group
2025. Epigenetic differences at immune and type 1 diabetes susceptibility genes in blood from young children after COVID-19 infection (PDF, 2,8 MB, nytt fönster).
Raffael Ott, Tarini Singh, Katharina Schütte-Borkovec, Marlon Scholz, Kristina Casteels, Gita Gemulla, Olga Kordonouri, Helena Elding Larsson, Agnieszka Szypowska, John A. Todd, Anette-G. Ziegler, Ezio Bonifacio.
2025. Genetics of circulating proteins in newborn babies at high risk of type 1 diabetes (PDF, 1,4 MB, nytt fönster)
Tutino M, Yu NY, Hatzikotoulas K, Park YC, Kreitmaier P, Katsoula G, Berner R, Casteels K, Elding Larsson H, Kordonouri O, Ołtarzewski M, Szypowska A, Ott R, Weiss A, Winkler C, Zapardiel-Gonzalo J, Petrera A, Hauck SM, Bonifacio E, Ziegler AG, Zeggini E.
2019. Oral insulin therapy for primary prevention of type 1 diabetes in infants with high genetic risk: the GPPAD-POInT (global platform for the prevention of autoimmune diabetes primary oral insulin trial) study protocol (PDF, 0,64 MB, nytt fönster).
Ziegler AG, Achenbach P, Berner R, Casteels K, Danne T, Gündert M, Hasford J, Hoffmann VS, Kordonouri O, Lange K, Elding Larsson H, Lundgren M, Snape MD, Szypowska A, Todd JA, Bonifacio E, GPPAD Study group
Comment: Screening for asymptomatic β-cell autoimmunity in young children
Ziegler AG, Hoffmann GF, Hasford J, Elding-Larsson H, Danne T, Berner R et al.
Lancet Adol. February 08, 2019. DOI:https://doi.org/10.1016/S2352-4642(19)30028-8
Screening for Type 1 Diabetes Risk in Newborns: The Freder1k Pilot Study in Saxony.
Hommel A, Haupt F, Delivani P, Winkler C, Stopsack M, Wimberger P, Nitzsche K, Heinke S, Naeke A, Ceglarek U, Thiery J, Bergert R, Stadthaus D, Groeger K, Heubner G, Schramm U, Dziambor U, Zirkel A, Kiess W, Mueller I, Lange K, Berner R, Bonifacio E, Ziegler AG; and the Freder1k Study Group. Horm Metab Res. 2018 Jan;50(1):44-49
2017. Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity (PDF, 0,24 MB, nytt fönster).
Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA. Diabetologia. 2017 Jan;60(1):35-38.
2016. Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease (PDF, 1,0 MB, nytt fönster).
Ziegler AG, Bonifacio E, Powers AC, Todd JA, Harrison LC, Atkinson MA. Diabetes. 2016 Nov;65(11):3233-3239.
2016. Primary prevention of beta-cell autoimmunity and type 1 diabetes – The Global Platform for the Prevention of Autoimmune Diabetes (GPPAD) perspectives (PDF, 0,87 MB, nytt fönster).
Ziegler AG, Danne T, Dunger DB, Berner R, Puff R, Kiess W, Agiostratidou G, Todd JA, Bonifacio E. Mol Metab. 2016 Feb 22;5(4):255-62.
2015. Staging presymptomatic type 1 diabetes: a scientific statement of JDRF, the Endocrine Society, and the American Diabetes Association (PDF, 1,1 MB, nytt fönster).
Insel RA, Dunne JL, Atkinson MA, Chiang JL, Dabelea D, Gottlieb PA, Greenbaum CJ, Herold KC, Krischer JP, Lernmark Å, Ratner RE, Rewers MJ, Schatz DA, Skyler JS, Sosenko JM, Ziegler AG. Diabetes Care. 2015 Oct;38(10):1964-74.
General population screening for type 1 diabetes: has its time come?
Insel RA, Dunne JL, Ziegler AG. Curr Opin Endocrinol Diabetes Obes. 2015 Aug;22(4):270-6
2013. Seroconversion to multiple islet autoantibodies and risk of progression to diabetes in children (PDF, 0,5 MB, nytt fönster).
Ziegler AG, Rewers M, Simell O, Simell T, Lempainen J, Steck A, Winkler C, Ilonen J, Veijola R, Knip M, Bonifacio E, Eisenbarth GS. JAMA. 2013 Jun 19;309(23):2473-9.